Outstanding young American instrumentalists form NYO2, a free orchestra program that comes together alongside the National Youth Orchestra of the United States of America (NYO-USA) and NYO Jazz each summer for intensive training and performance opportunities. NYO2 has a particular focus on recruiting musicians from communities underrepresented in classical music. Participating musicians have the opportunity to work closely with top players from American orchestras and conservatories during a residency at Purchase College, State University of New York.

In summer 2023, conductor Joseph Young leads the ensemble in its first-ever international residency and performances in the Dominican Republic with guest soloist Jennifer Koh.